CEFTAROLINE PACKAGE INSERT PDF

For Injection: Teflaro is supplied as mg or mg of sterile ceftaroline fosamil powder in single-dose, 20 mL clear glass. There is minimal potential for drug-drug interactions between TEFLARO and CYP substrates, inhibitors, or inducers; drugs known to undergo active renal . To reduce the development of drug-resistant bacteria and maintain the effectiveness of TEFLARO and other antibacterial drugs, TEFLARO should be used to.

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Arrived in ED with deep and extensive cellulitis on right leg. Therefore, these findings were not considered to be adverse. As ceftaroline does not appear to undergo significant hepatic metabolism, the systemic clearance of ceftaroline is not expected to be significantly affected by hepatic impairment.

Elixhauser A, Owens P. Request a representative now by filling ceftarolinee and sending the request form below. Infect Dis Clin Pract.

Carcinogenicity studies have inseet been conducted. Sign Up Log In Cancel. The safety and efficacy of Zinforo in children below the age of 2 months have not yet been established. Each vial contains ceftaroline fosamil acetic acid solvate monohydrate equivalent to mg ceftaroline fosamil.

Juvenile toxicity Intravenous bolus dosing of ceftaroline fosamil to suckling rats from post-natal day 7 to 20 was well tolerated at plasma exposures approximately 2-fold higher than those for paediatric patients.

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Genetic toxicology Ceftaroline fosamil and ceftaroline were clastogenic in an in vitro chromosomal aberration assay, however there was no evidence of mutagenic activity in an Ames test, mouse lymphoma and unscheduled DNA synthesis assay.

There is no experience with ceftaroline in the treatment of CAP in the following patient groups: Qualitative and quantitative composition 3. Furthermore, in vivo micronucleus assays in rat packaye mouse were negative.

By continuing, you are confirming that you have read the Indications and Usage. Arrived in ED with an abscess on the forearm that has worsened from a scrape. However, when ceftaroline was administered throughout pregnancy and lactation, there was no effect on pup weight or growth. In vitro studies have shown that ceftaroline is bactericidal and able to inhibit bacterial cell wall synthesis in methicillin-resistant Staphylococcus aureus MRSA and penicillin non-susceptible Streptococcus pneumoniae PNSP due to its affinity for the altered penicillin-binding proteins PBPs found in these organisms.

Zinforo 600 mg powder for concentrate for solution for infusion

Arrived in ED 48 hours ago with cellulitis on right arm. Infected surgical wound For illustrative purposes only. Clinical study experience with ceftaroline fosamil in patients with pre-existing inwert disorders is very limited. The mean terminal elimination half-life of ceftaroline in healthy adults is approximately 2. Immediate and severe hypersensitivity e.

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Reasons for being admitted to packagge hospital through the emergency department, Accessed August 11, Appropriate specimens for microbiological examination should be obtained in order to isolate and identify the causative pathogens and to determine their susceptibility to ceftaroline.

Therefore, interactions of ceftaroline with medicinal products that are substrates or inhibitors e. Please confirm that you are a healthcare professional in the United States.

TEFLARO® (ceftaroline fosamil) Dosing Information

Streptococcus pneumoniae including cases with concurrent pzckageStaphylococcus aureus methicillin-susceptible isolates onlyHaemophilus influenzaeKlebsiella pneumoniaeKlebsiella oxytocaand Escherichia coli. Pregnancy There are no or limited amount of data from the use of ceftaroline fosamil in pregnant women.

The following adverse reactions have been identified during clinical trials and post-marketing experience with Zinforo. Weight-based dosing is required for pediatric patients.

In vitro susceptibility data are intended for healthcare professionals only. Other important toxicologic findings noted in the rat and monkey included histopathologic changes in the bladder and spleen.